%0 Journal Article %T Lacking of palladin leads to multiple cellular events changes which contribute to NTD %A Chun-Ling Shen %A Hong-Xin Zhang %A Jian Fei %A Juan Tan %A Ling-Yun Tang %A Shun-Yuan Lu %A Wen-Ting Wu %A Xue-Jiao Chen %A Ying Kuang %A Zhu-Gang Wang %J Archive of "Neural Development". %D 2017 %R 10.1186/s13064-017-0081-6 %X The actin cytoskeleton-associated protein palladin plays an important role in cell motility, morphogenesis and adhesion. In mice, Palladin deficient embryos are lethal before embryonic day (E) 15.5, and exhibit severe cranial neural tube and body wall closure defects. However, the mechanism how palladin regulates the process of cranial neural tube closure (NTC) remains unknown %K Palladin %K Neural tube defect %K Cytoskeleton %K Proliferation %K Differentiation %K Apoptosis %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366166/