%0 Journal Article %T The first night effect in multiple sclerosis patients undergoing home-based polysomnography %A Christian Veauthier %A Friedemann Paul %A Gunnar Gaede %A Sophie K Piper %A Thomas Penzel %J Archive of "Nature and Science of Sleep". %D 2018 %R 10.2147/NSS.S176201 %X The first night effect (FNE) is a polysomnography (PSG) habituation effect in the first of several consecutive in-laboratory PSGs (I-PSGs). The FNE is caused by the discomfort provoked by electrodes and cables and the exposure to an unfamiliar environment. A reverse FNE (RFNE) with an improved sleep in the first night is characteristic of insomnia, presumably because the video PSG in the sleep laboratory leads to a decrease in the negatively toned cognitive activity. Therefore, two or more I-PSGs are required for an accurate diagnosis. Although the FNE is well documented in I-PSG, little is known about the FNE and the RFNE in home-based PSGs (H-PSGs) %K insomnia %K multiple sclerosis %K outpatient sleep studies %K polysomnography %K sleep latency %K wake after sleep onset %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207396/