%0 Journal Article
%T Epitope targeting with self-assembled peptide vaccines
%A Christopher H. Clegg
%A David F. Zeigler
%A Emily Gage
%A Richard Roque
%J Archive of "NPJ Vaccines".
%D 2019
%R 10.1038/s41541-019-0125-5
%X P8 peptide forms a heat stable trimeric coiled-coil. a Circular dichroism spectra: P8 was dissolved in phosphate-buffered saline and subjected to increasing temperature from 5£¿¡ãC to 95£¿¡ãC, followed by a return to 5£¿¡ãC (gray line). b Analytical ultracentrifugation spectrum of P8 showing monomer (0.76£¿S), trimer (1.78£¿S), and higher-order assemblies (>3£¿S). c Intensity-weighted dynamic light scattering spectrum showing major self-assembly (7£¿nm) and two minor assemblies (25 and 350£¿nm
%K Biotechnology
%K Immunology
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642127/