%0 Journal Article %T Development of tau PET Imaging Ligands and their Utility in Preclinical and Clinical Studies %A Dong Jin Kim %A Dong Soo Lee %A Seunggyun Ha %A Yoori Choi %A Yun Kyung Kim %A Yun-Sang Lee %J Archive of "Nuclear Medicine and Molecular Imaging". %D 2018 %R 10.1007/s13139-017-0484-7 %X a Illustration represents six tau isoforms expressed in human. The red box labeled with R1¡«R4, indicates microtubule-binding domain of tau. b Diagrammatic representation of tau conformation and NFT formation. Diverse NFT conformations can be formed depending on the composition of tau isoform %K Tau %K Alzheimer¡¯s disease %K Tauopathy %K Pet %K Imaging ligands %K Radiopharmaceutical %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777957/