%0 Journal Article
%T Injection of Botulinum Toxin for Preventing Salivary Gland Toxicity after PSMA Radioligand Therapy: an Empirical Proof of a Promising Concept
%A Aviral Singh
%A Christiane Schuchardt
%A Gerd Fabian Volk
%A Harshad Kulkarni
%A Mostafa Shahinfar
%A Richard P. Baum
%A Thomas Langbein
%J Archive of "Nuclear Medicine and Molecular Imaging".
%D 2018
%R 10.1007/s13139-017-0508-3
%X Axial fused (a, c) and sagittal reconstructed 3D (b, d) 68Ga-PSMA PET/CT images in a 63-year-old patient with advanced metastatic castration-resistant prostate cancer before (a, b) and 45 days after (c, d) multifocal, ultrasound-guided injections of a total of 80 units botulinum toxin A into the right parotid gland. The SUVmean of the radioligand in the injected parotid gland shows a highly significant decrease of up to 60% compared with the left side (c, d white arrows), especially in the pars profunda of the gland, and a decrease of up to 64%, but no significant change in the left parotid gland, compared with the baseline PET/CT study (a, b
%K Prostate cancer
%K PSMA radioligands
%K Salivary glands
%K Positron emission tomography
%K Botulinum toxin
%K Xerostomia
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777965/