%0 Journal Article
%T Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer
%A A Rix
%A D Doleschel
%A E Borkham-Kamphorst
%A E Fiegle
%A F Kiessling
%A R Weiskirchen
%A S Koletnik
%A W Lederle
%J Archive of "Neoplasia (New York, N.Y.)".
%D 2019
%R 10.1016/j.neo.2019.07.006
%K ARG1
%K arginase-1
%K COX-2
%K cyclooxygenase-2
%K CRC
%K colorectal cancer
%K CTLA-4
%K cytotoxic T-lymphocyte-associated protein 4
%K DCE-MRI
%K dynamic contrast enhanced MRI
%K FAP
%K fibroblast-activated protein
%K FOXP3
%K forkhead box protein P3
%K iNOS
%K inducible nitric oxide synthase
%K IFN-¦Ã
%K interferon- ¦Ã
%K MRC1
%K macrophage mannose receptor 1
%K PD-1
%K programmed death 1
%K PD-L1
%K programmed death-ligand 1
%K PDGF-B
%K platelet-derived growth factor B
%K PDGFR-¦Â
%K platelet-derived growth factor receptor ¦Â
%K p.i.
%K post-injection
%K s.c.
%K subcutaneous
%K TARC
%K thymus and activation regulated chemokine
%K TEM
%K Tie2+ macrophages
%K TGF-¦Â
%K transforming growth factor-¦Â
%K TIE2
%K tyrosine kinase with immunoglobulin-like and EGF-like domains 2
%K Treg cells
%K regulatory T cells
%K VEGF-A
%K vascular endothelial growth factor A
%K VEGFR2
%K vascular endothelial growth factor receptor 2
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700499/