%0 Journal Article %T Adaptive metabolic pattern biomarker for disease monitoring and staging of lung cancer with liquid biopsy %A Ana Fernandez-Carrascal %A Ana Olano-Daza %A Eduardo Garcia-Rico %A Luca Guerrini %A Manuel Garcia-Algar %A Neus Feliu %A Ramon A. Alvarez-Puebla %A Roger Guimera %A Wolfgang J. Parak %J Archive of "NPJ Precision Oncology". %D 2018 %R 10.1038/s41698-018-0059-9 %X Effects of oxygen on human PBMCs spiked with a tumor cell line. Flow cytometry of PBMCs obtained from human blood from a healthy donor sample spiked with A549 cells (1:100 ratio, cancer:healthy) as a function of the oxygen conditions. a normoxia; b hypoxia; and c hyperoxia. d Average 2NBDG fluorescence emission per cell for the different oxygen conditions. e Ratiometric differences in 2NBDG fluorescence emission for cancer cells (A549) and PBMCs (lymphocytes and monocytes) under the three oxygen conditions. FSC: forward-scattered ligh %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082903/