%0 Journal Article %T Parallels between vertebrate cardiac and cutaneous wound healing and regeneration %A Rebecca J. Richardson %J Archive of "NPJ Regenerative Medicine". %D 2018 %R 10.1038/s41536-018-0059-y %X Cutaneous wound healing in adult mouse. a Schematic showing method of inducing several (usually 2每4) punch biopsy full-thickness skin wounds to the back skin of a mouse. b每e Schematics describing the four main stages of cutaneous healing in adult mouse generally defined as: immediate responses including blood clot formation and neutrophil recruitment (0每2ˋh; b); inflammation involving neutrophil and monocyte recruitment from the peripheral circulation and activation of tissue-resident cells (1每72ˋh; c); re-epithelialization where keratinocytes proliferate and migrate to re-cover the wound, also coinciding with fibrotic granulation tissue formation, collagen deposition and angiogenic sprouting (3每10 days; d); and finally, the contraction of the wound by myofibroblasts, wound closure, resolution of inflammation and scar remodelling (14 days每months; e %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220283/