%0 Journal Article
%T Raman spectroscopic imaging for quantification of depth-dependent and local heterogeneities in native and engineered cartilage
%A A. Vinals Guitart
%A E. G. Evita
%A H. M. Zlotnick
%A J. P. St-Pierre
%A M. B. Albro
%A M. M. Stevens
%A M. S. Bergholt
%J Archive of "NPJ Regenerative Medicine".
%D 2018
%R 10.1038/s41536-018-0042-7
%X (a) Raw spectra of native and engineered cartilage. Raman spectroscopic image (univariate analysis) of ECM heterogeneities in 56-day cultured large engineered cartilage tissue construct (£¿6£¿mm£¿¡Á£¿3£¿mm) for (b) the full cross-section (10£¿¦Ìm spatial resolution) and (c) a localized peripheral region (1£¿¦Ìm resolution). Arrows represent media-exposed surfaces. (d) Raman spectroscopic image of natural depth dependent ECM heterogeneities in native articular cartilage (10£¿¦Ìm resolution). Arrow represents articular surfac
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807411/