%0 Journal Article
%T Protection Efficacy of C5A Against Vaginal and Rectal HIV Challenges in Humanized Mice
%A Aaron Kirchhoff
%A Angel Gandarilla
%A John A. Moss
%A Marc M. Baum
%A Philippe A. Gallay
%A Richard B. Pyles
%A Udayan Chatterji
%J Archive of "The Open Virology Journal".
%D 2018
%R 10.2174/1874357901812010001
%X In the absence of a vaccine, there is an urgent need for the identification of effective agents that prevent HIV transmission in uninfected individuals. Non-vaccine Biomedical Prevention (nBP) methods, such as topical or systemic pre-exposure prophylaxis (PrEP), are promising strategies to slow down the spread of AIDS
%K HIV transmission
%K Microbicide
%K Bone marrow/Liver/Thymus Mice
%K C5A
%K Vaginal challenge
%K Rectal challenge
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842390/