%0 Journal Article %T Suppl-1, M2: Hepatitis C Virus and Hepatocellular Carcinoma: Pathogenetic Mechanisms and Impact of Direct-Acting Antivirals %A Arnolfo Petruzziello %A Claudia Pinacchio %A Giuseppe Corano Scheri %A Ivan Schietroma %A Maura Statzu %A Vincenzo Vullo %J Archive of "The Open Virology Journal". %D 2018 %R 10.2174/1874357901812010016 %X Globally, between 64 and 103 million people are chronically infected with Hepatitis C virus (HCV), with more than 4.6 million people in the United States and is associated with more than 15.000 deaths annually. Chronic infection can result in cirrhosis and hepatocellular carcinoma %K HCV %K HCC %K DAA¡¯s %K Immunity %K Viral factors %K Chronic infection %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842384/