%0 Journal Article
%T Ocular Mucous Membrane Pemphigoid: Current State of Pathophysiology, Diagnostics and Treatment
%A Eszter Fodor
%A Francesco Sabatino
%A Hendrik P. N. Scholl
%A Nora Szentmary
%A Panagiotis Georgoudis
%A Samer Hamada
%A Sotiria Palioura
%A Zisis Gatzioufas
%J Archive of "Ophthalmology and Therapy".
%D 2019
%R 10.1007/s40123-019-0164-z
%X In the injury phase, autoantibodies are directed against conjunctival BM antigens, such as BP180, laminin 332 (laminin 5), collagen VII, and ¦Á6¦Â4 integrin [17]. The activated T cells generate specific B-cell clones, and these clones produce circulating autoantibodies (IgG and IgA) that bind to the specific BMZ component, initiate a type 2 hypersensitivity reaction, and activate the complement cascade (C3) [15]
%K Diagnostics
%K Mucous
%K Ocular pemphigoid
%K Pathophysiology
%K Treatment
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393250/