%0 Journal Article
%T RpbL12 Assists Catalysis by Correctly Positioning the Incoming Aminoacyl-tRNA in the A-Site of E. coli 70S Ribosomes
%A Codjo Hountondj
%A Fulbert K. Agbo¡¯Saga
%A Jean-Bernard Cr¨¦chet
%A Soria Baouz
%J Archive of "The Open Biochemistry Journal".
%D 2018
%R 10.2174/1874091X01812010113
%X We have recently demonstrated that Lys-65 of the 62GANK65 motif of E. coli RpbL12 was affinity labeled with a tRNA analogue, resulting in the loss of activity
%K E. coli ribosomal protein bL12
%K GGQ-like GAN motif of bL12
%K Lys-65 of bL12
%K Site-directed mutagenesis
%K Mechanism of peptide bond formation
%K Aminoacyl-tRNA
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110070/