%0 Journal Article
%T Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation
%A Bingwei Ye
%A Chunhong Yan
%A Han-Fei Ding
%A Hongjuan Cui
%A Jane Ding
%A Liqun Yang
%A Mengling Liu
%A Yunhong Zha
%A Zheng Dong
%J Archive of "Oncogenesis".
%D 2019
%R 10.1038/s41389-018-0112-0
%X a¨Cc Kdm6b expression is downregulated in mouse neuroblastoma sphere-forming cells as measured by microarray (a), qRT-PCR (b, error bars, s.d., n£¿=£¿3), and immunoblotting (c), in comparison with primary tumor cells. ¦Á-tubulin levels are shown as loading control (c). Data were analyzed using two-tailed Student¡¯s t-test. d¨Ce Low KDM6B expression is associated with reduced event-free survival in neuroblastoma patients (d), high-risk neuroblastoma (e, left panel), and advanced stages of the tumors (e, right panel). Patient data analyses (d¨Ce) were conducted online (R2 Genomics Analysis and Visualization Platform), and the resulting figures and log-rank test (d) and Student¡¯s t-test (e) p values were downloaded. **p£¿<£¿0.01; ***p£¿<£¿0.00
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328563/