%0 Journal Article %T Chromatin remodelling and epigenetic state regulation by non-coding RNAs in the diseased heart %A F. De Majo %A M. Calore %J Archive of "Non-coding RNA Research". %D 2018 %R 10.1016/j.ncrna.2018.02.003 %X Epigenetics refers to all the changes in phenotype and gene expression which are not due to alterations in the DNA sequence. These mechanisms have a pivotal role not only in the development but also in the maintenance during adulthood of a physiological phenotype of the heart. Because of the crucial role of epigenetic modifications, their alteration can lead to the arise of pathological conditions %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084839/