%0 Journal Article
%T Utility of the JAX Clinical Knowledgebase in capture and assessment of complex genomic cancer data
%A Cara M. Statz
%A Sara E. Patterson
%A Susan M. Mockus
%A Taofei Yin
%J Archive of "NPJ Precision Oncology".
%D 2019
%R 10.1038/s41698-018-0073-y
%X The JAX-CKB complex molecular profile. a Structure of the relationship between the complex molecular profile (top) and therapy response, via the molecular profile response. b Example of a molecular profile response associated with a complex profile. This complex molecular profile comprises two alterations: EGFR E746_A750del and MET amplification, which was demonstrated in a clinical study (evidence source) to be resistant (response type) to Osimertinib (therapy) in a lung adenocarcinoma (tumor type) patien
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333807/