%0 Journal Article
%T Relative contributions of adipose-resident CD146+ pericytes and CD34+ adventitial progenitor cells in bone tissue engineering
%A Aaron W. James
%A Bruno Peault
%A Carolyn A. Meyers
%A Jiajia Xu
%A Kristen Broderick
%A Lei Zhang
%A Leslie Chang
%A Min Lee
%A Yiyun Wang
%J Archive of "NPJ Regenerative Medicine".
%D 2019
%R 10.1038/s41536-018-0063-2
%X Microcomputed tomographic (microCT) imaging and analysis of calvarial defect healing with CD146+ pericytes or CD34+ adventitial cells, alone or in combination. a 3D coronal section reconstructions of calvarial defect site among ¡°no scaffold¡± control, ¡°scaffold alone¡° control, or three different cell treatment groups. ¡°Pericyte¡± group consisted of 2.5£¿¡Á£¿105 CD146+CD34£¿CD45£¿CD31£¿ pericytes. ¡°Adventitial¡± group consisted of 2.5£¿¡Á£¿105 CD34+CD146£¿CD45£¿CD31£¿ adventitial cells. ¡°Pericyte£¿+£¿Adventitial¡± group consisted of a 50%/50% split between each cell type (1.25£¿¡Á£¿105 adventitial cells and 1.25£¿¡Á£¿105 pericytes). b¨Cd MicroCT quantification of bone repair in calvarial defects within each treatment group, 8 weeks postoperative. b Bone volume, c bone volume/ttissue volume, and d Bone fractional area. *P£¿<£¿0.05, **P£¿<£¿0.01 in comparison with ¡°no scaffold¡± group. N£¿=£¿46 bone defects per treatment grou
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323123/