%0 Journal Article
%T Functionally and morphologically damaged mitochondria observed in auditory cells under senescence-inducing stress
%A Chisato Fujimoto
%A Ken Hayashi
%A Shinichi Iwasaki
%A Tatsuya Yamasoba
%A Teru Kamogashira
%J Archive of "NPJ Aging and Mechanisms of Disease".
%D 2017
%R 10.1038/s41514-017-0002-2
%X Short exposure to H2O2 induces a decrease of population doubling in a dose-dependent manner, but does not affect the cell viability in HEI-OC1 cells. a Population doubling time. Population doubling experiments were performed in duplicate. b Cell viability. Cell viability was determined by trypan blue staining at the indicated times after short exposure (1£¿h) with H2O2 (0£¿¦ÌM, 100£¿¦ÌM, 300£¿¦ÌM, and 1£¿mM). All values are showed as mean£¿¡À£¿SD from three or more independent studies, n£¿=£¿6 per group. *P£¿<£¿0.0
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445612/