%0 Journal Article
%T Periodic Acid-Schiff Staining Parallels the Immunoreactivity Seen By Direct Immunofluorescence in Autoimmune Skin Diseases
%A Ana Maria Abreu Velez
%A Michael S Howard
%A Yulieth Alexandra Upegui Zapata
%J Archive of "North American Journal of Medical Sciences".
%D 2016
%R 10.4103/1947-2714.179132
%X In many countries and laboratories, techniques such as direct immunofluorescence (DIF) are not available for the diagnosis of skin diseases. Thus, these laboratories are limited in the full diagnoses of autoimmune skin diseases, vasculitis, and rheumatologic diseases. In our experience with these diseases and the patient's skin biopsies, we have noted a positive correlation between periodic acid-Schiff (PAS) staining and immunofluorescence patterns; however, these were just empiric observations. In the current study, we aim to confirm these observations, given the concept that the majority of autoantibodies are glycoproteins and should thus be recognized by PAS staining
%K Autoimmune vasculitis
%K bullous pemphigoid
%K cutaneous drug reactions
%K direct immunofluorescence (DIF)
%K lupus erythematosus (LE)
%K periodic acid-Schiff (PAS)
%K periodic acid-Schiff staining
%K pemphigus vulgaris
%K skin autoimmune blistering diseases
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821094/