%0 Journal Article
%T Pharmacological Modulation of Vagal Nerve Activity in Cardiovascular Diseases
%A Longzhu Liu
%A Ming Zhao
%A Weijin Zang
%A Xiaojiang Yu
%J Archive of "Neuroscience Bulletin".
%D 2019
%R 10.1007/s12264-018-0286-7
%X Methods and indices used to evaluate vagal activity in cardiovascular disease. Vagus activity can be evaluated by (I) measurement of the vagal discharge (image adapted from Lu Y et al. [27]); (II) autonomic tone and intrinsic heart rate; (III) HRV and BRS; (IV) cardiac autonomic nerves and cholinergic nerve distribution; and (V) detection of the release of ACh into the circulation (image adapted from Zhao M et al. [6]). ACh, acetylcholine; BRS, baroreflex sensitivity; HPLC, high performance liquid chromatography; HRV, heart rate variability; PSYM, parasympathetic; SYM, sympathetic
%K Cardiovascular disease
%K Cholinergic drugs
%K Muscarinic receptor
%K ¦Á7-nACh receptor
%K Vagus nerve
%K Vagomimetic drugs
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357265/