%0 Journal Article %T Treatment strategies and outcomes in patients with non-ST-elevation acute coronary syndrome in the Netherlands %A J. J. Piek %A P. Damman %J Archive of "Netherlands Heart Journal". %D 2019 %R 10.1007/s12471-018-1218-x %X Acute coronary syndrome (ACS) is predominantly caused by acute luminal narrowing due to sudden thrombus formation or plaque haemorrhage imposed on an atherosclerotic plaque [1]. A luminal thrombus forms as a direct consequence of plaque rupture or erosion. The initial electrocardiogram can be used to differentiate ST-elevation myocardial infarction (STEMI) and non-ST-elevation acute coronary syndrome (NSTE-ACS). Patients with STEMI are characterised by a complete and persistent occlusion of a large epicardial coronary artery and are best managed with immediate revascularisation by primary percutaneous coronary intervention [2]. Primary percutaneous coronary intervention (PCI) for STEMI is associated with a reduction in mortality compared with other reperfusion strategies [3] %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352624/