%0 Journal Article
%T Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia
%A Anjen Chenn
%A Christoph J¨¹schke
%A Eric J. Huang
%A Jennifer Rakotomamonjy
%A Keling Zang
%A Louis F. Reichardt
%A Molly Brunner
%J Archive of "Neural Development".
%D 2017
%R 10.1186/s13064-017-0085-2
%X In developing tissues, cell polarity and tissue architecture play essential roles in the regulation of proliferation and differentiation. During cerebral cortical development, adherens junctions link highly polarized radial glial cells in a neurogenic niche that controls their behavior. How adherens junctions regulate radial glial cell polarity and/or differentiation in mammalian cortical development is poorly understood
%K Cortical development
%K Adherens junctions
%K Apicobasal polarity
%K Cell fate
%K Primary cilia
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422985/