%0 Journal Article
%T An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites
%A Eleonora de Klerk
%A Laurens Grossouw
%A Muhammad Riaz
%A Peter A. C. ¡¯t Hoen
%A Soheil Yousefi
%A Tooba Abbassi-Daloii
%A Vered Raz
%J Archive of "NPJ Aging and Mechanisms of Disease".
%D 2017
%R 10.1038/s41514-017-0007-x
%X Schematic representation of PAS switches. Switches in PAS utilization are shown with arrows: upstream switches are depicted in blue and downstream switches in red. An upstream switch is most often from distal 3¡ä-UTR to any internal gene regions (intron, exon, and internal 3¡ä-UTR), and a downstream switch is most often from any internal gene regions to distal 3¡ä-UTR. Switches between tandem PASs in the distal 3¡ä-UTR are also shown. The most prominent switches are depicted with continues line. PASs are depicted with vertical bars, the gene regions, exon (E), intron (I), and 3¡ä-UTR are indicated. Illustrated are the most abundant switch possibilitie
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445584/