%0 Journal Article
%T Hyperbaric Oxygen Therapy Suppresses Apoptosis and Promotes Renal Tubular Regeneration After Renal Ischemia/Reperfusion Injury in Rats
%A Heihachi Migita
%A Narantsog Choijookhuu
%A Shigenori Yoshitake
%A Yoshihiro Tange
%A Yoshitaka Hishikawa
%J Archive of "Nephro-urology Monthly".
%D 2016
%R 10.5812/numonthly.34421
%X Renal ischemia/reperfusion (I/R) injury remains a major cause of acute kidney injury (AKI), in addition to I/R injury-induced tissue inflammation, necrosis and apoptosis. Hyperbaric oxygen therapy (HBO) is defined as a treatment in which a patient is intermittently exposed to 100% oxygen pressurized to a pressure above sea level (> 2.0 atmospheres absolute (ATA), 1.0 ATA = 760 mmHg). It has been used in a number of medical conditions with a proven efficacy in a limited number of disorders. However, the effects of HBO therapy on apoptosis and proliferative activity after I/R injury have not been fully understood
%K Hyperbaric Oxygen Therapy
%K Ischemia/Reperfusion Injury
%K Apoptosis
%K Rats
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780282/