%0 Journal Article
%T Use of blood biomarkers to screen for obstructive sleep apnea
%A Aliya S Ferouz-Colborn
%A Amabelle B Cruz
%A Armaghan Azad
%A Dennis Hwang
%A Edith Mensah-Osman
%A Jiuliu Lu
%A John S Riley
%A Jon-Erik C Holty
%A Michael K Samoszuk
%A Nadir Ishag Osman
%A Paula C Southwick
%A Qing Li
%A Richard K Bogan
%A Rohit Budhiraja
%A Susan Redline
%A Susann Podolak
%A Wesley Elon Fleming
%A Yang Bai
%J Archive of "Nature and Science of Sleep".
%D 2018
%R 10.2147/NSS.S164488
%X Obstructive sleep apnea (OSA) is a highly prevalent disorder associated with increased risk for cardiovascular disease, diabetes, and other chronic conditions. Unfortunately, up to 90% of individuals with OSA remain without a diagnosis or therapy. We assess the relationship between OSA and blood biomarkers, and test the hypothesis that combinations of markers provide a characteristic OSA signature with diagnostic screening value. This validation study was conducted in an independent cohort in order to replicate findings from a prior feasibility study
%K obstructive sleep apnea
%K OSA
%K screening
%K diagnosis
%K biomarkers
%K CRP
%K HbA1c
%K erythropoietin
%K EPO
%K uric acid
%K IL-6
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005302/