%0 Journal Article
%T Sustained release of decorin to the surface of the eye enables scarless corneal regeneration
%A Aaron Ng
%A Ann Logan
%A Chairut Vareechon
%A Eric Pearlman
%A Gibran Butt
%A Graham R. Wallace
%A Gurpreet Chouhan
%A Kristian Brock
%A Liam M. Grover
%A Lisa J. Hill
%A Nicholas M. Barnes
%A Rachel C. Vincent
%A Richard J. A. Moakes
%A Richard L. Williams
%A Saaeha Rauz
%A Serena Abbondante
%J Archive of "NPJ Regenerative Medicine".
%D 2018
%R 10.1038/s41536-018-0061-4
%X Processing and intrinsic material properties of the gellan-based fluid gel eye drop. a Schematic showing the production of the fluid gel: where the initial sol is continuously processed under shear whilst being cooled to form ¡°ribbon-like¡± gelled entities shown using (i) transmission microscopy and (ii) scanning electron microscopy. b Time-dependent viscosity profiles obtained for the gellan eye drop, highlighting a degree of thixotropy. c The fluid gel being dispensed from the eye dropper packaging (gel has been stained blue so as to be visible in the photograph). d Small deformation rheology data obtained at a single frequency (1£¿Hz, 0.5% strain) as a function of time. Data show the evolution of an elastic network post-shearing resulting in a transition from liquid to solid-like behavior. e Anterior segment OCT images showing the ocular surface before fluid gel application (top image) and post application (bottom image). Images demonstrate a uniform layer that covers the entirety of the ocular surfac
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303295/