%0 Journal Article %T Suppression of olfactory signal transduction by insecticides %A Hiroko Takeuchi %A Takashi Kurahashi %J Archive of "NPJ Science of Food". %D 2019 %R 10.1038/s41538-019-0042-z %X Cell responses to vapours from bananas. a Evaluation of banana flavour. Forty evaluators choose the stronger banana-like scent one from two bananas (paired test). For analyses, the score for selected banana was set to 1 and another 0. When the evaluator selected neither, both were 0. There is a significant statistical difference by Welch¡¯s t test (*p£¿<£¿0.05). b Scheme of cell stimulation; two puffer pipettes contained stimulants originated from type a or type b bananas. Sliced bananas were placed in containers for 3£¿h and volatile molecules in containers were adsorbed into filter papers that were wetted with normal Ringer¡¯s solution and were adhered to the back of the lid. Solutions were then squeezed and applied to single olfactory receptor cells (ORCs) under the voltage clamp. c Current responses to stimulants from strong smelling bananas (type a). d Current responses to stimulants from weak smelling bananas (type b). b, c were obtained from the same ORC. The same banana samples (type a and b) were used for human psychology tests and cell experiments throughout a¨C %K Cyclic nucleotide-gated cation channels %K Inhibition %K Olfactory receptors %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550234/