%0 Journal Article %T Comparative Pharmacokinetic Profiles of Three Protoberberine-type Alkaloids from Raw and Bile-processed Rhizoma coptidis in Heat Syndrome Rats %A Chen Gui-rong %A Chen Yue %A Gao Hui %A Jing Wang %A Lv Jia %A Yuan Zi-min %J Archive of "Pharmacognosy Magazine". %D 2017 %R 10.4103/0973-1296.197632 %X The Bile-processed Rhizoma coptidis (BRC), which has a colder drug property than Rhizoma coptidis (RC), is widely used for the treatment of heat syndrome. We compared the pharmacokinetics of the protoberberine-type alkaloids in BRC and RC in rats with heat syndrome to elucidate the bile-processing mechanism %K Bile-processed %K heat syndrome %K pharmacokinetic profiles %K protoberberine-type alkaloids %K Rhizoma coptidis %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307914/