%0 Journal Article
%T A Review on the Pharmacological Activities and Phytochemicals of Alpinia officinarum (Galangal) Extracts Derived from Bioassay-Guided Fractionation and Isolation
%A Aida Maryam Basri
%A Hussein Taha
%A Norhayati Ahmad
%J Archive of "Pharmacognosy Reviews".
%D 2017
%R 10.4103/phrev.phrev_55_16
%X The rhizomes of Alpinia officinarum Hance have been used conventionally for the treatment of various ailments, triggering a wide interest from the scientific research community on this ethnomedicinal plant. This review summarizes the phytochemical and pharmacological properties of the extracts and fractions from A. officinarum, a plant species of the Zingiberaceae family. Different parts of the plant 每 leaves, roots, rhizomes, and aerial parts 每 have been extracted in various solvents 每 methanol, ethanol, ethyl acetate, hexane, dichloromethane, aqueous, chloroform, and petroleum ether, using various techniques 每 Soxhlet extraction, maceration, ultrasonication, and soaking, whereas fractionation of the plant extracts involves the solvent每solvent partition method. The extracts, fractions, and isolated compounds have been studied for their biological activities 每 antioxidant, antibacterial, anti-inflammatory, anticancer, antiproliferative, inhibition of enzymes, as well as the inhibition of nitric oxide production. More findings on A. officinarum are certainly important to further develop potential bioactive drug compounds
%K Alpinia officinarum
%K ethnomedicinal plant
%K lesser galangal
%K pharmacological
%K phytochemicals
%K Zingiberaceae
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414456/