%0 Journal Article
%T Protective Effect of Withania coagulans Fruit Extract on Cisplatin-induced Nephrotoxicity in Rats
%A Apurva Joshi
%A Siva Hemalatha
%A Sonam Sharma
%J Archive of "Pharmacognosy Research".
%D 2017
%R 10.4103/pr.pr_1_17
%X Fruits of Withania coagulans (Solanaceae) reported to possess several bioactive compounds as curative agents for various clinical conditions. Cisplatin is a chemotherapeutic drug to treat sarcomas, carcinomas, lymphomas, cervical cancer, germ cell tumors, etc. The major factor that limits its clinical use is its dose-dependent nephrotoxicity
%K Cisplatin
%K DNA fragmentation assay
%K nephroprotective
%K withaferin A
%K Withania coagulans
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717787/