%0 Journal Article
%T Preparation of Platinum Nanoparticles-Graphene Modified Electrode and Selective Determination of Rutin
%A Shu-Hong Yu
%A Guang-Chao Zhao
%J International Journal of Electrochemistry
%D 2012
%I Hindawi Publishing Corporation
%R 10.4061/2012/431253
%X Platinum nanoparticles were electrodeposited on graphene modified glassy carbon electrode to form a modified electrode, and the electrode was characterized with scanning electron microscopy (SEM). At the modified electrode, rutin, a natural flavonoid, shows a couple of well-defined redox peaks, which is corresponded to the reduction and reoxidation of rutin. The electrochemical behaviors of rutin at the electrode were investigated, and the results indicated that the electrode reaction is controlled by adsorption process. Under the optimal conditions, the peak currents of differential pulse voltammetry (DPV) increased linearly with the rutin concentration in the range from to £¿M with a limit of detection of £¿M. The as-prepared electrode was successfully used for the selective determination of rutin in tablet, displaying a potential application of graphene composite modified electrode. 1. Introduction Rutin (quercetin-3-rutinoside, which chemical structure is shown in Figure 1) is a natural flavonoid with a wide of biochemical and pharmacological activities, including antigenotoxic, anti-inflammatory, antioxidant effects, antibacterial, antiviral, cytoprotective, and antiprotozoal properties, hypolipidaemic and anticonvulsive effects, and anticarcinogenic [1¨C6]. The interest in using rutin in cosmetic and pharmaceutical formulations is to enhance their antioxidant and vasoprotective properties, promoting relief of the symptoms of lymphatic and venous insufficiency. Up to now, methods for investigation of rutin have included spectrophotometry [7], capillary electrophoresis [8], chemiluminescence [9], HPLC [10], and electrochemical methods [11, 12]. Among these methods, electrochemical method is simple and sensitive. However, the sensitivity and selectivity of electrochemical method usually depends on the electrode material. Figure 1: Rutin chemical structure. Metal nanoparticles have attracted considerable attention due to their conspicuous physical and chemical properties [13, 14]. Previous investigates suggested that platinum nanoparticles have a good electrocatalytic activity among metal nanoparticles. So, platinum nanoparticles have widely been applied in many fields, such as electrocatalytic oxidation of formic acid and methanol [15, 16]. However, in order to utilize its function, platinum nanoparticles must be immobilized on supported materials, such as carbon materials and other conducting or semiconducting materials. Graphene is a new form of carbon material with carbon atoms parked in a two-dimensional honey lattice, which has attracted a
%U http://www.hindawi.com/journals/ijelc/2012/431253/