%0 Journal Article %T The influence of CYP3A5 polymorphisms on haloperidol treatment in patients with alcohol addiction %A Dmitry Alekseevich Sychev %A Elena Anatolievna Grishina %A Evgeny Alekseevich Bryun %A Kristina Anatolievna Ryzhikova %A Ludmila Mikhailovna Savchenko %A Mikhail Sergeevich Zastrozhin %A Valery Valerievich Smirnov %J Archive of "Pharmacogenomics and Personalized Medicine". %D 2018 %R 10.2147/PGPM.S144503 %X Isoenzymes CYP2D6 and CYP3A4, the activity of which varies widely, are involved in metabolism of haloperidol and may influence its profile of efficacy and safety %K haloperidol %K CYP3A5* %K CYP3A %K cortisol %K alcohol use disorder %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749387/