%0 Journal Article
%T Varicella Zoster Virus and Large Vessel Vasculitis, the Absence of an Association
%A Alexander Blandford
%A Alexandra Villa-Forte
%A Alison Clifford
%A Charis Eng
%A Deborah A. Wilson
%A Douglas Johnston
%A Edward Soltesz
%A Eric Roselli
%A Gary S. Hoffman
%A Gary W. Procop
%A Gosta Pettersson
%A Julian D. Perry
%A Lars Svensson
%A Leonard H. Calabrese
%A Lisa Lystad
%J Archive of "Pathogens and Immunity".
%D 2017
%R 10.20411/pai.v2i2.196
%X It is controversial whether microorganisms play a role in the pathogenesis of large and medium vessel vasculitides (eg, giant cell arteritis [GCA], Takayasu arteritis [TAK] and focal idiopathic aortitis [FIA]). Recent studies have reported the presence of Varicella Zoster Virus (VZV) within formalin-fixed, paraffin-embedded temporal arteries and aortas of about three-quarters or more of patients with these conditions, and in a minority of controls. In a prospective study, we sought to confirm these findings using DNA extracted from vessels that were harvested under surgically aseptic conditions and snap frozen
%K Aorta and temporal artery biopsies
%K Varicella Zoster Virus
%K Large Vessel Vasculitis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531613/