%0 Journal Article
%T Identification of Protease Specificity Using Biotin-Labeled Substrates
%A Hiroyuki Yamamoto
%A Michio Kimura
%A Syota Saito
%A Yoshikazu Sawaguchi
%J Archive of "The Open Biochemistry Journal".
%D 2017
%R 10.2174/1874091X01711010027
%X Proteolysis constitutes a major post-translational modification. For example, proteases regulate the activation or inactivation of various proteins, such as enzymes, growth factors, and peptide hormones. Proteases have substrate specificity, and protease expression regulates the specific and regional activation or inactivation of several functional proteins
%K Protease specificity
%K Mass spectrometry
%K Biotin-labeled peptides
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418938/