%0 Journal Article
%T CYP3A and CYP2C19 activity in urine in relation to CYP3A4, CYP3A5, and CYP2C19 polymorphisms in Russian peptic ulcer patients taking omeprazole
%A Dmitriy A Sychev
%A Elena A Grishina
%A Kristina A Ryzhikova
%A Natalia P Denisenko
%A Valeriy V Smirnov
%A Zhanna M Sizova
%A Zhannet A Sozaeva
%J Archive of "Pharmacogenomics and Personalized Medicine".
%D 2018
%R 10.2147/PGPM.S159708
%X Proton pump inhibitors (PPIs) are metabolized by cytochrome P450. CYP2C19 is the main isoenzyme for the majority of PPI, whereas CYP3A family is a secondary enzyme for PPI biotransformation
%K pharmacogenetics
%K phenotyping
%K metabolomics
%K proton pump inhibitor
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014385/