%0 Journal Article
%T The integrated high-resolution reflection-mode photoacoustic and fluorescence confocal microscopy
%A Caimei Cui
%A Chengbo Liu
%A Jianhua Chen
%A Jiuling Liao
%A Liang Song
%A Longchao Chen
%A Rubo Ding
%A Wei Zheng
%A Xiaojing Gong
%A Zhiqiang Pang
%J Archive of "Photoacoustics".
%D 2019
%R 10.1016/j.pacs.2019.02.001
%X A dual modality microscopy with the highest imaging resolution reported so far based on reflection-mode photoacoustic and confocal fluorescence is presented in this study. The unique design of the imaging head of the microscope makes it highly convenient for scalable high-resolution imaging by simply switching the optical objectives. The submicron resolution performance of the system is demonstrated via in vivo imaging of zebrafish, normal mouse ear, and a xenograft tumor model inoculated in the mouse ear. The imaging results confirm that the presented dual-modality microscopy imaging system could play a vital role in observing model organism, studying tumor angiogenesis and assessment of antineoplastic drugs
%K 00-01
%K 99-00 Photoacoustic microscopy
%K Confocal microscopy
%K Multimodal imaging
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423349/