%0 Journal Article
%T Photoacoustic imaging for monitoring periodontal health: A first human study
%A Ali Hariri
%A Casey Chen
%A Ching-Yu Lin
%A Colman Moore
%A Jesse V. Jokerst
%A Joan B. Sanchez
%A Parish Sedghizadeh
%A Sreenivas Koka
%A Yuting Bai
%J Archive of "Photoacoustics".
%D 2018
%R 10.1016/j.pacs.2018.10.005
%X The gold-standard periodontal probe is an aging tool that can detect periodontitis and monitor gingival health but is highly error-prone, does not fully characterize the periodontal pocket, and causes pain. Photoacoustic imaging is a noninvasive technique that can address these limitations. Here, a range of ultrasound frequencies between 16¨C40£¿MHz were used to image the periodontium and a contrast medium based on cuttlefish ink was used to label the pockets. A 40£¿MHz ultrasound frequency could spatially resolve the periodontal anatomy, including tooth, gum, gingival margin, and gingival thickness of tooth numbers 7¨C10 and 22¨C27. The photoacoustic-ultrasound measurements were more precise (0.01£¿mm) than those taken with physical probes by a dental hygienist. Furthermore, the full geometry of the pockets could be visualized with relative standard deviations of 10% (n£¿=£¿5). This study shows the potential for non-invasive monitoring of periodontal health with photoacoustic-ultrasound imaging in the dental clinic
%K Photoacoustic imaging
%K Periodontal disease
%K Diagnosis
%K Gingival thickness
%K Pocket depth
%K Periodontal charting
%K Melanin nanoparticles
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226559/