%0 Journal Article
%T Epidemiology and management of healthcare-associated bloodstream infections in non-neutropenic immunosuppressed patients: a review of the literature
%A Nursel Calik Basaran
%A Sibel Ascioglu
%J Archive of "Therapeutic Advances in Infectious Disease".
%D 2017
%R 10.1177/2049936117733394
%X Advancements in medicine have led to a considerable increase in the proportion of patients living with severe chronic diseases, malignancies, and HIV infections. Most of these conditions are associated with acquired immune-deficient states and treatment-related immunosuppression. Although infections as a result of neutropenia have long been recognized and strategies for management were developed, non-neutropenic immunosuppression has been overlooked. Recently, community-acquired infections in patients with frequent, significant exposure to healthcare settings and procedures have been classified as ¡®healthcare-associated infections¡¯ since they are more similar to hospital-acquired infections. Most of the non-neutropenic immunosuppressed patients have frequent contact with the healthcare system due to their chronic and severe diseases. In this review, we focus on the healthcare-associated bloodstream infections in the most common non-neutropenic immunosuppressive states and provide an update of the recent evidence for the management of these infections
%K bloodstream infection
%K immunosuppression
%K non-neutropenic
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896868/