%0 Journal Article
%T Behavioral thermoregulation in older adults with cardiovascular co-morbidities
%A Blair D. Johnson
%A Christopher L. Chapman
%A David Hostler
%A Gregory L. Coleman
%A James R. Sackett
%A Suman Sarker
%A Zachary J. Schlader
%J Archive of "Temperature: Multidisciplinary Biomedical Journal".
%D 2018
%R 10.1080/23328940.2017.1379585
%X We tested the hypotheses that older adults with cardiovascular co-morbidities will demonstrate greater changes in body temperature and exaggerated changes in blood pressure before initiating thermal behavior. We studied twelve healthy younger adults (Younger, 25 ¡À 4 y) and six older adults (¡®At Risk¡¯, 67 ¡À 4 y) taking prescription medications for at least two of the following conditions: hypertension, type II diabetes, hypercholesterolemia. Subjects underwent a 90-min test in which they voluntarily moved between cool (18.1 ¡À 1.8¡ãC, RH: 29 ¡À 5%) and warm (40.2 ¡À 0.3¡ãC, RH: 20 ¡À 0%) rooms when they felt ¡®too cool¡¯ (C¡úW) or ¡®too warm¡¯ (W¡úC). Mean skin and intestinal temperatures and blood pressure were measured. Data were analyzed as a change from pretest baseline. Changes in mean skin temperature were not different between groups at C¡úW (Younger: +0.2 ¡À 0.8¡ãC, ¡®At Risk¡¯: +0.7 ¡À 1.8¡ãC, P = 0.51) or W¡úC (Younger: +2.7 ¡À 0.6¡ãC, ¡®At Risk¡¯: +2.9 ¡À 1.9¡ãC, P = 0.53). Changes in intestinal temperature were not different at C¡úW (Younger: 0.0 ¡À 0.1¡ãC, ¡®At Risk¡¯: +0.1 ¡À 0.2, P = 0.11), but differed at W¡úC (-0.1 ¡À 0.2¡ãC vs. +0.1 ¡À 0.3¡ãC, P = 0.02). Systolic pressure at C¡úW increased (Younger: +10 ¡À 9 mmHg, ¡®At Risk¡¯: +24 ¡À 17 mmHg) and at W¡úC decreased (Younger: £¿4 ¡À 13 mmHg, ¡®At Risk¡¯: -23 ¡À 19 mmHg) to a greater extent in ¡®At Risk¡¯ (P ¡Ü 0.05). Differences were also apparent for diastolic pressure at C¡úW (Younger: £¿2 ¡À 4 mmHg, ¡®At Risk¡¯: +17 ¡À 23 mmHg, P < 0.01), but not at W¡úC (Younger Y: +4 ¡À 13 mmHg, ¡®At Risk¡¯: £¿1 ¡À 6 mmHg, P = 0.29). Despite little evidence for differential control of thermal behavior, the initiation of behavior in ¡®at risk¡¯ older adults is preceded by exaggerated blood pressure responses
%K blood pressure
%K cutaneous vascular conductance
%K metabolic heat production
%K skin blood flow
%K sweat rate
%K thermal discomfort
%K thermoregulatory behavior
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902208/