%0 Journal Article
%T Proteomic analysis of gemcitabine-resistant pancreatic cancer cells reveals that microtubule-associated protein 2 upregulation associates with taxane treatment
%A Bart Kok
%A Btissame El Hassouni
%A Connie R. Jimenez
%A Elisa Giovannetti
%A Geert Kazemier
%A Hanneke W.M. van Laarhoven
%A Kenneth P. Olive
%A Maarten F. Bijlsma
%A Niccola Funel
%A Sander R. Piersma
%A Tessa Ya Sung Le Large
%A Thang V. Pham
%J Archive of "Therapeutic Advances in Medical Oncology".
%D 2019
%R 10.1177/1758835919841233
%X Chemoresistance hampers the treatment of patients suffering from pancreatic ductal adenocarcinoma (PDAC). Here we aimed to evaluate the (phospho)proteome of gemcitabine-sensitive and gemcitabine-resistant PDAC cells to identify novel therapeutic targets and predictive biomarkers
%K gemcitabine
%K nab-paclitaxel
%K pancreatic cancer
%K phosphoproteomics
%K proteomics
%K resistance
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535709/