%0 Journal Article %T Gut feeling: randomized controlled trials of probiotics for the treatment of clinical depression: Systematic review and meta-analysis %A Allan H. Young %A Anthony J. Cleare %A James M. Stone %A Syed Yawar Zaidi %A Viktoriya Nikolova %J Archive of "Therapeutic Advances in Psychopharmacology". %D 2019 %R 10.1177/2045125319859963 %X Recently the gut microbiota has attracted significant interest in psychiatric research due to the observed bidirectional gut¨Cbrain communication. A growing body of evidence from preclinical work has suggested that probiotics may be effective in reducing stress and anxiety and alleviating low mood. It is unclear to what extent these effects are seen in clinical populations. We aimed to identify all published evidence on the efficacy of probiotics as treatment for depression in clinically depressed populations %K depression %K probiotics %K randomized controlled trial %K systematic review %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595633/