%0 Journal Article %T Safety and efficacy of nilotinib in routine clinical practice in patients with chronic myeloid leukemia in chronic or accelerated phase with resistance or intolerance to imatinib: results from the NOVEL study %A Cheng-Hwai Tzeng %A Cheng-Shyong Chang %A Chih-Yi Hsieh %A Ching-Yuan Kuo %A Chinjune Lin %A Clinton Lai %A Darko Miljkovic %A Jih-Luh Tang %A Li-Yaun Bai %A Ming-Chih Chang %A Po-Nan Wang %A Sheng-Fung Lin %A Tran-Der Tan %A Tsai-Yun Chen %A Wen-Li Hwang %A Yeu-Chin Chen %J Archive of "Therapeutic Advances in Hematology". %D 2018 %R 10.1177/2040620718756603 %X Nilotinib, a second-generation tyrosine kinase inhibitor (TKI), is approved for the treatment of patients with chronic myeloid leukemia (CML) in many countries, including Taiwan. Though a number of controlled clinical trials have demonstrated the safety and efficacy of nilotinib, studies assessing the safety and efficacy of nilotinib in routine clinical practice are limited %K chronic myeloid leukemia %K clinical trial %K imatinib-resistant %K nilotinib %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843102/