%0 Journal Article
%T Mast cell degranulation impairs pneumococcus clearance in mice via IL-6 dependent and TNF-¦Á independent mechanisms
%A Jichao Wang
%A Jing Yang
%A Jurong Yan
%A Si Sun
%A Wenchun Xu
%A Xuemei Zhang
%A Yibing Yin
%A Yujuan He
%A Yulan Qiu
%J Archive of "The World Allergy Organization Journal".
%D 2019
%R 10.1016/j.waojou.2019.100028
%X Mast cells participate in immune responses by releasing potent immune system modifiers via degranulation. Due to currently reported controversial roles of mast cells in Streptococcus pneumoniae infections, this study aimed to determine the role and mechanism of mast cells in clearing S. pneumoniae in mice
%K Degranulation
%K Inflammatory response
%K Mast cell
%K Streptococcus pneumoniae
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479162/