%0 Journal Article
%T ¦ÁT-catenin: A developmentally dispensable, disease-linked member of the ¦Á-catenin family
%A Annette S. Flozak
%A Cara J. Gottardi
%A Erik E. Rabin
%A Lorena A. Ostilla
%A Sergio E. Chiarella
%J Archive of "Tissue Barriers".
%D 2018
%R 10.1080/21688370.2018.1463896
%X ¦Á-Catenins are actin-filament binding proteins and critical subunits of the cadherin-catenin cell-cell adhesive complex. They are found in nominally-defined epithelial (E), neural (N), and testis (T) forms transcribed from three distinct genes. While most of ¦Á-catenin research has focused on the developmentally essential founding member, ¦ÁE-catenin, this review discusses recent studies on ¦ÁT-catenin (CTNNA3), a developmentally dispensable isoform that is emerging as relevant to cardiac, allergic and neurological diseases
%K cadherins
%K cell-cell adhesion
%K catenins
%K actin
%K signaling
%K asthma
%K neurological
%K cardiomyopathy
%K adherens junctions
%K Biology of epithelial barriers
%K Desmosomes
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179130/