%0 Journal Article %T Biochemical Measurements of Free Opsin in Macular Degeneration Eyes: Examining the 11-CIS Retinal Deficiency Hypothesis of Delayed Dark Adaptation (An American Ophthalmological Society Thesis) %A Anne Hanneken %A Jennifer Johnson %A Masahiro Kono %A Thomas Neikirk %J Archive of "Transactions of the American Ophthalmological Society". %D 2017 %X To test the hypothesis that delayed dark adaptation in patients with macular degeneration is due to an excess of free unliganded opsin (apo-opsin) and a deficiency of the visual chromophore, 11-cis retinal, in rod outer segments %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572981/