%0 Journal Article %T Moving toward a prevention strategy for osteoporosis by giving a voice to a silent disease %A Carrie A. Karvonen-Gutierrez %A Erin M. R. Bigelow %A Karl J. Jepsen %A Melissa Ramcharan %A Stephen H. Schlecht %J Archive of "Women's Midlife Health". %D 2016 %R 10.1186/s40695-016-0016-0 %X Sagittal sections derived from 3-dimensional nanoComputed Tomography images (nanotom-s; phoenix|x-ray, GE Sensing & Inspection Technologies, GmbH; Wunstorf, Germany) of cadaveric proximal femurs for two women, one 24 years old and the other 54 years old, convey how bone loss occurs non-uniformly with aging and predominantly in the region used to measure aBMD with DEXA. Maintaining bone strength is analogous to maintaining a bridge, where all critical structural components must be recognized and targeted to keep the structure intact and functioning to prevent a catastrophic failure even %K Menopausal transition %K Bone %K Strength %K BMD %K Osteoporosis %K Biomechanics %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035036/