%0 Journal Article %T Building barriers %A Kursad Turksen %J Archive of "Tissue Barriers". %D 2017 %R 10.1080/21688370.2017.1400866 %X Formation of tissue barriers starts in early development where it is critical for normal cell fate selection, differentiation and organogenesis. Barrier maintenance is critical to the ongoing function of organs during adulthood and aging. Dysfunctional tissue barrier formation and function at any stage of the organismal life cycle underlies many disease states %K aging %K Claudin %K development %K disease %K tissue barrier %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788411/