%0 Journal Article
%T YRNAs overexpression and potential implications in allergy
%A Asunci¨®n Garc¨ªa-S¨¢nchez
%A Catalina Sanz
%A Elena Marcos-Vadillo
%A Fernando Marques-Garc¨ªa
%A Ignacio D¨¢vila
%A Juan Carlos Trivi£¿o
%A Marien Pascual
%A Mar¨ªa Isidoro-Garc¨ªa
%A Miguel Estrav¨ªs
%A Sergio Roa
%J Archive of "The World Allergy Organization Journal".
%D 2019
%R 10.1016/j.waojou.2019.100047
%X Small non-coding RNAs (snRNAs) develop important functions related to epigenetic regulation. YRNAs are snRNAs involved in the initiation of DNA replication and RNA stability that regulate gene expression. They have been related to autoimmune, cancer and inflammatory diseases but never before to allergy. In this work we described for the first time in allergic patients the differential expression profile of YRNAs, their regulatory mechanisms and their potential as new diagnostic and therapeutic targets
%K Allergy
%K Epigenetics
%K Expression
%K ncRNA
%K Transcriptomics
%K YRNAs
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664241/