%0 Journal Article
%T Roles of functional catechol-O-methyltransferase genotypes in Chinese patients with Parkinson¡¯s disease
%A Jiujiang Liu
%A Qin Xiao
%A Shaoqing Xu
%A Xiaodong Yang
%A Yiwei Qian
%J Archive of "Translational Neurodegeneration".
%D 2017
%R 10.1186/s40035-017-0081-9
%X Recent studies have found that the functional catechol-O-methyltransferase (COMT) gene may be associated with the susceptibility to and pharmacotherapy of Parkinson¡¯s disease (PD). In this case¨Ccontrol study, we investigated the most common functional COMT gene haplotypes that had been shown to influence COMT enzymatic activity and the association of the single and combined COMT haplotypes with clinical symptoms and pharmacotherapy in Chinese patients with PD
%K Parkinson¡¯s disease
%K COMT
%K SNP
%K Pharmacotherapy
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405521/