%0 Journal Article
%T The Midlife WomenĄŻs Health Study ¨C a study protocol of a longitudinal prospective study on predictors of menopausal hot flashes
%A Ayelet Ziv-Gal
%A Howard A. Zacur
%A Jodi A. Flaws
%A Lisa Gallicchio
%A Rebecca L. Smith
%A Susan R. Miller
%J Archive of "Women's Midlife Health".
%D 2017
%R 10.1186/s40695-017-0024-8
%X The MWHS study was designed to test the hypothesis that obesity is associated with hot flashes through: a) early ovarian follicle loss/failure, b) selected genetic polymorphisms in the genes that encode enzymes that synthesize and degrade sex steroids and/or the receptors that allow tissues to respond to sex steroids, or c) mechanisms involving early follicle loss/failure, altered sex steroid hormone levels, and genetic polymorphisms in genes that encode enzymes that synthesize and degrade sex steroids and/or receptors that respond to sex steroids (this part of the study is yet to be conducted
%K Hot flash
%K Menopausal transition
%K BMI
%K Cigarette smoking
%K Race
%K Study protocol
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300019/